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Ver el documento (formato PDF)   Biondic, Miriana Carla.  "Fotoquímica de ß-Carbolinas en soluciones orgánicas diluidas"  (1996)
Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires
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Abstract:
In this work the photochemical behavior of full aromatic b-carbolines (nor-harmane, harmane, harmine and harmol) and two 3,4-dihydro b-carbolines (harmaline and harmalol) was studied. For the first time the UV absorption, emission and excitation spectra in organic solutions were described as well as on solid supports (silica gel, paper) and on powdered sample. The K of the complexation equilibrium between the full aromatic b-carbolines with alcohols forming a 1:2 adducts were measured and the pKa and pKa* in acetonitrile were determined by means of electronic absorption and fluorescence spectroscopy. Considering that these compounds are markedly fluorescent their behavior in the presence of CCl4 and other halomethanes (CH2Cl2, CHCl3, CH2BrCH2Br, CHBr3 and CBr4) which act as quenchers using either EtOH, iso-PrOH or MeCN as solvents was studied. We concluded that this quenching is dynamic and may take place through the formation of an exciplex followed by an electron transfer from the excited b-carboline to the halogenated compound starting the photochemical reaction. When a solution of either of these alkaloids (10-3 M) was irradiated in the presence of CCl4 in a protic organic solvent, the main product obtained, with more than 98% yield, was the hydrochloride. Besides, the gc-MS analysis showed traces of carboalcoxy and chloro-derivatives.%The feasibility of an exciton or a photon single electron transfer mechanism is discussed and parameters such as DGote, Ksv, kq, DG‡, DG‡(0), l, and E0ox were calculated using the Rehm-Weller, Marcus and Stern-Volmer models.%The quantum yield of photobleaching in different solvents was determined relative to the disappearance of harmane in EtOH-CCl4, which in turn was determined using potassium ferrioxalate as actinometer.
Registro:
Título : Fotoquímica de ß-Carbolinas en soluciones orgánicas diluidas    
Autor : Biondic, Miriana Carla
Director : Erra Balsells, Rosa
Año : 1996
Editor : Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires
Filiación : Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales
Departamento de Química Orgánica
Grado obtenido : Doctor en Ciencias Químicas
Ubicación : Preservación - http://digital.bl.fcen.uba.ar/gsdl-282/cgi-bin/library.cgi?a=d&c=tesis&d=Tesis_2831_Biondic
Idioma : Español
Area Temática : Química / Química Orgánica
Palabras claves : ß-CARBOLINAS; FOTOQUIMICA DE ß-CARBOLINAS; ß-CARBOLINAS-TETRACLORURO DE CARBONO; EQUILIBRIO ACIDO-BASE DE ß-CARBOLINAS; ESPECTROS ELECTRONICOS DE ß-CARBOLINAS; ß-CARBOLINES; ß-CARBOLINES-PHOTOCHEMISTRY; ß-CARBOLINES-CARBON-TETRACHLORIDE; ß-CARBOLINES-ACID-BASE EQUILIBRIUM; ß-CARBOLINES-ELECTRONIC SPECTRA
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