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Abstract:

Traditional approaches for risk assessment of ischemic heart disease (IHD) are based on the physiological consequences of an epicardial coronary stenosis. Of note, normal coronary arteries or nonobstructive coronary artery disease (CAD) is a common finding in women with signs and symptoms of ischemia. Therefore, assessment of risk based on a coronary stenosis approach may fail in women. Positron emission tomography (PET) quantifies absolute myocardial blood flow (MBF) which may help to elucidate other mechanisms involved such as endothelial dysfunction and alterations in the smooth muscle cell relaxation responsible for IHD in women. The objective of the present review is to describe the current state of the art of PET imaging in assessing IHD in women with nonobstructive CAD. © Cardiovascular Diagnosis and Therapy. All rights reserved.

Registro:

Documento: Artículo
Título:Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
Autor:Campisi, R.; Marengo, F.D.
Filiación:Department of Nuclear Medicine and Cardiovascular Imaging, Diagnóstico Maipú, Av. Maipú 1668, Vicente-López, Buenos-Aires, B1602ABQ, Argentina
Department of Nuclear Medicine, Instituto Argentino de Diagnóstico y Tratamiento S.A., Buenos Aires, Argentina
Laboratorio de Fisiología y Biología Molecular, Instituto de Fisiología, Biología Molecular y Neurociencias (CONICET), Departamento de Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Coronary flow reserve (CFR); Ischemic heart disease (IHD); Positron emission tomography (PET); Women; atherosclerosis; clinical assessment; coronary artery disease; diagnostic accuracy; endothelial dysfunction; heart muscle blood flow; human; intermethod comparison; ischemic heart disease; microangiopathy; myocardial perfusion imaging; positron emission tomography; prognosis; Review; risk assessment; single photon emission computed tomography; women's health
Año:2017
Volumen:7
Número:2
Página de inicio:196
Página de fin:205
DOI: http://dx.doi.org/10.21037/cdt.2017.04.08
Título revista:Cardiovascular Diagnosis and Therapy
Título revista abreviado:Cardiovasc. Diagn. Theer.
ISSN:22233652
Registro:http://digital.bl.fcen.uba.ar/collection/paper/document/paper_22233652_v7_n2_p196_Campisi

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Citas:

---------- APA ----------
Campisi, R. & Marengo, F.D. (2017) . Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography. Cardiovascular Diagnosis and Therapy, 7(2), 196-205.
http://dx.doi.org/10.21037/cdt.2017.04.08
---------- CHICAGO ----------
Campisi, R., Marengo, F.D. "Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography" . Cardiovascular Diagnosis and Therapy 7, no. 2 (2017) : 196-205.
http://dx.doi.org/10.21037/cdt.2017.04.08
---------- MLA ----------
Campisi, R., Marengo, F.D. "Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography" . Cardiovascular Diagnosis and Therapy, vol. 7, no. 2, 2017, pp. 196-205.
http://dx.doi.org/10.21037/cdt.2017.04.08
---------- VANCOUVER ----------
Campisi, R., Marengo, F.D. Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography. Cardiovasc. Diagn. Theer. 2017;7(2):196-205.
http://dx.doi.org/10.21037/cdt.2017.04.08