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enzyme specificity
59
"POLAR-guided signalling complex assembly and localization drive asymmetric cell division" (2018) Houbaert, A.;Zhang, C.;Tiwari, M. (...)Russinova, E. Nature. 563(7732):574-578
"CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5" (2018) Repetto, M.V.;Winters, M.J.;Bush, A. (...)Colman-Lerner, A. Molecular Cell. 69(6):938-952.e6
"Short linear motif core and flanking regions modulate retinoblastoma protein binding affinity and specificity" (2018) Palopoli, N.; Foutel, N.S.G.; Gibson, T.J.; Chemes, L.B. Protein Engineering, Design and Selection. 31(3):69-77
"PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase" (2016) Reyes, A.M.;Vazquez, D.S.;Zeida, A. (...)Trujillo, M. Free Radical Biology and Medicine. 101:249-260
"Steered Molecular Dynamics Methods Applied to Enzyme Mechanism and Energetics" (2016) Ramírez, C.L.; Martí, M.A.; Roitberg, A.E. Methods in Enzymology. 578:123-143
"Akt/PKB: One kinase, many modifications" (2015) Risso, G.;Blaustein, M.;Pozzi, B. (...)Srebrow, A. Biochemical Journal. 468(2):203-214
"Molecular Basis of Hydroperoxide Specificity in Peroxiredoxins: The Case of AhpE from Mycobacterium tuberculosis" (2015) Zeida, A.;Reyes, A.M.;Lichtig, P. (...)Trujillo, M. Biochemistry. 54(49):7237-7247
"Molecular Basis of Hydroperoxide Specificity in Peroxiredoxins: The Case of AhpE from Mycobacterium tuberculosis" (2015) Zeida, A.;Reyes, A.M.;Lichtig, P. (...)Trujillo, M. Biochemistry. 54(49):7237-7247
"Enzymatic synthesis of bile acid derivatives and biological evaluation against Trypanosoma cruzi" (2015) García Liñares, G.;Antonela Zígolo, M.;Simonetti, L. (...)Baldessari, A. Bioorganic and Medicinal Chemistry. 23(15):4804-4814
"Functional Analysis Of A Mosquito Short-Chain Dehydrogenase Cluster" (2013) Mayoral, J.G.;Leonard, K.T.;Nouzova, M. (...)Turjanski, A.G. Archives of Insect Biochemistry and Physiology. 82(2):96-115
"Lysine transporters in human trypanosomatid pathogens" (2012) Inbar, E.;Canepa, G.E.;Carrillo, C. (...)Pereira, C.A. Amino Acids. 42(1):347-360
"Oligomerization studies show that the kinase domain of the tomato pollen receptor kinase LePRK2 is necessary for interaction with LePRK1" (2012) Salem, T.M.;Barberini, M.L.;Wengier, D.L. (...)Muschietti, J. Plant Physiology and Biochemistry. 53:40-45
"Functional characterization of residues involved in redox modulation of maize photosynthetic NADP-Malic enzyme activity" (2012) Alvarez, C.E.;Detarsio, E.;Moreno, S. (...)Drincovich, M.F. Plant and Cell Physiology. 53(6):1144-1153
"Topology and dynamics of the zebrafish segmentation clock core circuit" (2012) Schröter, C.;Ares, S.;Morelli, L.G. (...)Oates, A.C. PLoS Biology. 10(7):11
"Oxidizing substrate specificity of Mycobacterium tuberculosis alkyl hydroperoxide reductase E: Kinetics and mechanisms of oxidation and overoxidation" (2011) Reyes, A.M.;Hugo, M.;Trostchansky, A. (...)Trujillo, M. Free Radical Biology and Medicine. 51(2):464-473
"Juvenile hormone synthesis: "esterify then epoxidize" or " epoxidize then esterify" ? Insights from the structural characterization of juvenile hormone acid methyltransferase" (2011) Defelipe, L.A.;Dolghih, E.;Roitberg, A.E. (...)Turjanski, A.G. Insect Biochemistry and Molecular Biology. 41(4):228-235
"Biocatalytic synthesis of chiral N-(2-hydroxyalkyl)-acrylamides" (2011) Monsalve, L.N.; Rustoy, E.M.; Baldessari, A. Biocatalysis and Biotransformation. 29(2-3):87-95
"Characterization of substrates that have a differential effect on Saccharomyces cerevisiae protein kinase A holoenzyme activation" (2010) Galello, F.; Portela, P.; Moreno, S.; Rossi, S. Journal of Biological Chemistry. 285(39):29770-29779
"Substrate stereo-specificity in tryptophan dioxygenase and indoleamine 2,3-dioxygenase" (2010) Capece, L.;Arrar, M.;Roitberg, A.E. (...)Estrin, D.A. Proteins: Structure, Function and Bioinformatics. 78(14):2961-2972
"The serine/arginine-rich protein SF2/ASF regulates protein sumoylation" (2010) Pelisch, F.;Gerez, J.;Druker, J. (...)Srebrow, A. Proceedings of the National Academy of Sciences of the United States of America. 107(37):16119-16124
"Molecular basis of coupled protein and electron transfer dynamics of cytochrome c in biomimetic complexes" (2010) Alvarez-Paggi, D.;Martín, D.F.;Debiase, P.M. (...)Murgida, D.H. Journal of the American Chemical Society. 132(16):5769-5778
"Conformational and electronic effects on the regioselectivity of the glycosylation of different anomers of N-dimethylmaleoyl-protected glucosamine acceptors" (2008) Bohn, M.L.; Colombo, M.I.; Rúveda, E.A.; Stortz, C.A. Organic and Biomolecular Chemistry. 6(3):554-561
"The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid β peptide: Implications for Alzheimer disease pathogenesis" (2008) Llovera, R.E.;De Tullio, M.;Alonso, L.G. (...)Castaño, E.M. Journal of Biological Chemistry. 283(25):17039-17048
"A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis" (2008) Schoijet, A.C.;Miranda, K.;Girard-Dias, W. (...)Alonso, G.D. Journal of Biological Chemistry. 283(46):31541-31550
"Nitric Oxide Reactivity with Globins as Investigated Through Computer Simulation" (2008) Marti, M.A.;Capece, L.;Bidon-Chanal, A. (...)Estrin, D.A. Methods in Enzymology. 437:477-498
"Two new dialkoxycarbonylated nucleosides obtained through a regioselective enzymatic alcoholysis" (2007) Capello, M.; Imanishi, L.; Iglesias, L.E.; Iribarren, A.M. Biotechnology Letters. 29(8):1217-1220
"Inhibition of cholinesterase activity by azinphos-methyl in two freshwater invertebrates: Biomphalaria glabrata and Lumbriculus variegatus" (2006) Kristoff, G.; Guerrero, N.V.; de D'Angelo, A.M.P.; Cochón, A.C. Toxicology. 222(3):185-194
"TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi" (2006) Alonso, G.D.; Schoijet, A.C.; Torres, H.N.; Flawiá, M.M. Molecular and Biochemical Parasitology. 145(1):40-49
"A high-throughput screening for phosphatases using specific substrates" (2005) Senn, A.M.; Wolosiuk, R.A. Analytical Biochemistry. 339(1):150-156
"Characterization and in vitro expression patterns of extracellular degradative enzymes from non-pathogenic binucleate Rhizoctonia AG-G" (2005) MacHinandiarena, M.F.;Wolski, E.A.;Barrera, V. (...)Andreu, A.B. Mycopathologia. 159(3):441-448
"Glycosphingolipids in Plasmodium falciparum: Presence of an active glucosylceramide synthase" (2004) Couto, A.S.;Caffaro, C.;Uhrig, M.L. (...)Erra-Balsells, R. European Journal of Biochemistry. 271(11):2204-2214
"Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi" (2004) D'Angelo, M.A.;Sanguineti, S.;Reece, J.M. (...)Flawiá, M.M. Biochemical Journal. 378(1):63-72
"Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo" (2004) Agustí, R.;París, G.;Ratier, L. (...)de Lederkremer, R.M. Glycobiology. 14(7):659-670
"Activation of JNK by Epac Is Independent of Its Activity as a Rap Guanine Nucleotide Exchanger" (2003) Hochbaum, D.;Tanos, T.;Ribeiro-Neto, F. (...)Coso, O.A. Journal of Biological Chemistry. 278(36):33738-33746
"Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases" (2003) Portal, D.;Lobo, G.S.;Kadener, S. (...)Torres, H.N. Molecular and Biochemical Parasitology. 127(1):9-21
"Rat kidney porphobilinogen deaminase kinetics: Detection of enzyme-substrate complexes" (2002) Noriega, G.; Mattei, G.; Batlle, A.; Juknat, A.A. International Journal of Biochemistry and Cell Biology. 34(10):1230-1240
"In vivo and in vitro phosphorylation of two isoforms of yeast pyruvate kinase by protein kinase A" (2002) Portela, P.; Howell, S.; Moreno, S.; Rossi, S. Journal of Biological Chemistry. 277(34):30477-30487
"One-pot biocatalyzed preparation of substituted amides as intermediates of pharmaceuticals" (2001) Baldessari, A.; Mangone, C.P. Journal of Molecular Catalysis - B Enzymatic. 11(4-6):335-341
"Histamine H2 receptor desensitization: Involvement of a select array of G protein-coupled receptor kinases" (2001) Shayo, C.;Fernandez, N.;Legnazzi, B.L. (...)Davio, C. Molecular Pharmacology. 60(5):1049-1056
"Arginine kinase of the flagellate protozoa Trypanosoma cruzi: Regulation of its expression and catalytic activity" (2001) Alonso, G.D.;Pereira, C.A.;Remedi, M.S. (...)Flawiá, M.M. FEBS Letters. 498(1):22-25
"α-Difluoromethylornithine-resistant cell lines obtained after one-step selection of Leishmania mexicana promastigote cultures" (1997) Sánchez, C.P.;Mucci, J.;González, N.S. (...)Algranati, I.D. Biochemical Journal. 324(3):847-853
"Regulation of Ca2+/calmodulin-dependent protein kinase from" (1996) Cruzi, T.; Ogueta, S.; Intosh, G.M.; Téllez-Iñon, Ma.T. Molecular and Biochemical Parasitology. 78(1-2):171-183
"delta-Aminolevulinic acid uptake is mediated by the gamma-aminobutyric acid-specific permease UGA4." (1996) Bermúdez Moretti, M.; Correa García, S.; Ramos, E.; Batlle, A. Cellular and molecular biology (Noisy-le-Grand, France). 42(4):519-523
"Glutamate:4,5‐dioxovaleric acid transaminase from Euglena gracilis Kinetic studies" (1989) LOMBARDO, M.E.; ARAUJO, L.S.; JUKNAT, A.A.; BATLLE, A.M.d.C. European Journal of Biochemistry. 182(3):657-660
"The separation and properties of two phosphoprotein phosphatases from the dimorphic fungus Mucor rouxii" (1984) Seigelchifer, M.A.; Passeron, S. Archives of Biochemistry and Biophysics. 229(1):403-413
"Studies on potato tuber phosphorylase-catalyzed reaction in the absence of an exogenous acceptor. I. Characterization and properties of the enzyme" (1981) Sivak, M.N.; Tandecarz, J.S.; Cardini, C.E. Archives of Biochemistry and Biophysics. 212(2):525-536
"Lipid-bound sugars in Rhizobium meliloti" (1980) Tolmasky, M.E.; Staneloni, R.J.; Ugalde, R.A.; Leloir, L.F. Archives of Biochemistry and Biophysics. 203(1):358-364