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cancer inhibition
38
"Inhibition of Notch signaling attenuates pituitary adenoma growth in Nude mice" (2019) Zubeldía-Brenner, L.;De Winne, C.;Perrone, S. (...)Becu-Villalobos, D. Endocrine-Related Cancer. 26(1):13-29
"Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk" (2018) Orozco, C.A.;Martinez-Bosch, N.;Guerrero, P.E. (...)Navarro, P. Proceedings of the National Academy of Sciences of the United States of America. 115(16):E3769-E3778
"Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis article" (2018) Gueron, G.;Anselmino, N.;Chiarella, P. (...)Vazquez, E. Cell Death and Disease. 9(2)
"In vivo hemin conditioning targets the vascular and immunologic compartments and restrains prostate tumor development" (2017) Jaworski, F.M.;Gentilini, L.D.;Gueron, G. (...)Vazquez, E.S. Clinical Cancer Research. 23(17):5135-5148
"Angiotensin-(1-7) counteracts the transforming effects triggered by angiotensin II in breast cancer cells" (2017) Cambados, N.;Walther, T.;Nahmod, K. (...)Schere-Levy, C. Oncotarget. 8(51):88475-88487
"Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model" (2017) Marostica, L.L.;de Barros, A.L.B.;Oliveira, J. (...)Simões, C.M.O. Toxicology and Applied Pharmacology. 329:272-281
"Biological relevance of Hsp90-binding immunophilins in cancer development and treatment" (2016) Mazaira, G.I.;Camisay, M.F.;De Leo, S. (...)Galigniana, M.D. International Journal of Cancer. 138(4):797-808
"Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549" (2016) Silva, I.T.;Geller, F.C.;Persich, L. (...)Simões, C.M.O. Investigational New Drugs. 34(2):139-148
"In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B" (2015) Silva, I.T.;Carvalho, A.;Lang, K.L. (...)Ludwig, S. PLoS ONE. 10(2)
"Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549" (2015) Marostica, L.L.;Silva, I.T.;Kratz, J.M. (...)Simões, C.M.O. Chemical Research in Toxicology. 28(10):1949-1960
"RSUME inhibits VHL and regulates its tumor suppressor function" (2015) Gerez, J.;Tedesco, L.;Bonfiglio, J.J. (...)Arzt, E. Oncogene. 34(37):4855-4866
"Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation" (2015) Ahmad, S.;Hewett, P.W.;Fujisawa, T. (...)Ahmed, A. Thrombosis and Haemostasis. 113(2):329-337
"Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice" (2014) Moiola, C.P.;Luca, P.D.;Zalazar, F. (...)De Siervi, A. Clinical Cancer Research. 20(15):4086-4095
"Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors" (2014) Croci, D.O.;Cerliani, J.P.;Dalotto-Moreno, T. (...)Rabinovich, G.A. Cell. 156(4):744-758
"Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn" (2013) Silva, I.T.;Teixeira, C.R.;Lang, K.L. (...)Simões, C.M.O. International Journal of Cancer Research. 9(2):54-68
"Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments" (2012) Soldati, R.;Berger, E.;Zenclussen, A.C. (...)Fest, S. International Journal of Cancer. 131(5):1131-1141
"Oral administration of fluoxetine alters the proliferation/apoptosis balance of lymphoma cells and up-regulates T cell immunity in tumor-bearing mice" (2011) Frick, L.R.;Rapanelli, M.;Arcos, M.L.B. (...)Genaro, A.M. European Journal of Pharmacology. 659(2-3):265-272
"H2O2 scavenging inhibits G1/S transition by increasing nuclear levels of p27KIP1" (2011) Ibañez, I.L.;Policastro, L.L.;Tropper, I. (...)Durán, H. Cancer Letters. 305(1):58-68
"Inhibitory effects of antivascular endothelial growth factor strategies in experimental dopamine-resistant prolactinomas" (2011) Luque, G.M.;Perez-Millán, M.I.;Ornstein, A.M. (...)Becu-Villalobos, D. Journal of Pharmacology and Experimental Therapeutics. 337(3):766-774
"Kinetic recognition of the retinoblastoma tumor suppressor by a specific protein target" (2011) Chemes, L.B.; Sánchez, I.E.; De Prat-Gay, G. Journal of Molecular Biology. 412(2):267-284
"Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas" (2009) Wargon, V.;Helguero, L.A.;Bolado, J. (...)Lanari, C. Breast Cancer Research and Treatment. 116(3):449-460
"Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo" (2009) Schaaf, C.;Shan, B.;Buchfelder, M. (...)Renner, U. Endocrine-Related Cancer. 16(4):1339-1350
"Cellular inactivation and antitumor efficacy of a new zinc phthalocyanine with potential use in photodynamic therapy" (2008) Vittar, N.B.R.;Prucca, C.G.;Strassert, C. (...)Rivarola, V.A. International Journal of Biochemistry and Cell Biology. 40(10):2192-2205
"Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft" (2007) Gazzaniga, S.;Bravo, A.I.;Guglielmotti, A. (...)Wainstok, R. Journal of Investigative Dermatology. 127(8):2031-2041
"Bone morphogenetic protein-4 inhibits corticotroph tumor cells: Involvement in the retinoic acid inhibitory action" (2006) Giacomini, D.;Páez-Pereda, M.;Theodoropoulou, M. (...)Arzt, E. Endocrinology. 147(1):247-256
"Signaling processes in tumoral neuroendocrine pituitary cells as potential targets for therapeutic drugs" (2005) Paez-Pereda, M.;Giacomini, D.;Echenique, C. (...)Arzt, E. Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5(3):259-267
"The HPV16 E7 Viral Oncoprotein Self-Assembles into Defined Spherical Oligomers" (2004) Alonso, L.G.;García-Alai, M.M.;Smal, C. (...)De Prat-Gay, G. Biochemistry. 43(12):3310-3317
"Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer " (2004) Salatino, M.;Schillaci, R.;Proietti, C.J. (...)Elizalde, P.V. Medicina. 64(2):129-134
"Dehydroepiandrosterone treatment attenuates oestrogen-induced pituitary hyperplasia" (2002) Suárez, C.; García Tornadú, I.; Khalil, W.; Becu-Villalobos, D. Journal of Endocrinology. 174(3):447-454
"Preparation and cytotoxicity toward cancer cells of mono(arylimino) derivatives of β-lapachone" (2001) Di Chenna, P.H.;Benedetti-Doctorovich, V.;Baggio, R.F. (...)Burton, G. Journal of Medicinal Chemistry. 44(15):2486-2489
"Nerve growth factor and retinoic acid inhibit proliferation and invasion in thyroid tumor cells" (2000) Páez Pereda, M.;Missale, C.;Grübler, Y. (...)Stalla, G.K. Molecular and Cellular Endocrinology. 167(1-2):99-106
"Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells" (1997) Fernanda Ledda, M.;Adris, S.;Bravo, A.I. (...)Podhajcer, O.L. Nature Medicine. 3(2):171-176
"Enhancement of aminolevulinic acid based photodynamic therapy by adriamycin" (1997) Casas, A.; Fukuda, H.; Riley, P.; Del C. Batlle, A.M. Cancer Letters. 121(1):105-113
"Effect of a gonadotropin releasing hormone analog on an experimental ovarian tumor: Direct and indirect actions" (1995) Lux-Lantos, V.A.R.; Thyssen, S.M.; Chamson, A.; Libertun, C. Life Sciences. 57(3):291-300