Registro:

Referencias:

• Ammoun, S., Holmqvist, T., Shariatmadari, R., Oonk, H.B., Detheux, M., Parmentier, M., Akerman, K.E., Kukkonen, J.P., Distinct recognition of OX1 and OX2 receptors by orexin peptides (2003) J Pharmacol Exp Ther, 305, pp. 507-514
• Arihara, Z., Takahashi, K., Murakami, O., Totsune, K., Sone, M., Satoh, F., Ito, S., Mouri, T., Immunoreactive orexin-A in human plasma (2001) Peptides, 22, pp. 139-142
• Barreiro, M.L., Pineda, R., Gaytan, F., Archanco, M., Burrell, M.A., Castellano, J.M., Hakovirta, H., Tena-Sempere, M., Pattern of orexin expression and direct biological actions of orexin-A in rat testis (2005) Endocrinology, 146, pp. 5164-5175
• Blanco, M., Gallego, R., Garcia-Caballero, T., Dieguez, C., Beiras, A., Cellular localization of orexins in human anterior pituitary (2003) Histochem Cell Biol, 120, pp. 259-264
• Brogan, R.S., Grove, K.L., Smith, M.S., Differential regulation of leptin receptor but not orexin in the hypothalamus of the lactating rat (2000) J Neuroendocrinol, 12, pp. 1077-1086
• Buffenstein, R., Poppitt, S.D., McDevitt, R.M., Prentice, A.M., Food intake and the menstrual cycle: A retrospective analysis, with implications for appetite research (1995) Physiol Behav, 58, pp. 1067-1077
• Cai, X.J., Denis, R., Vernon, R.G., Clapham, J.C., Wilson, S., Arch, J.R., Williams, G., Food restriction selectively increases hypothalamic orexin-B levels in lactating rats (2001) Regul Pept, 97, pp. 163-168
• Campbell, R.E., Grove, K.L., Smith, M.S., Gonadotropin-releasing hormone neurons coexpress orexin 1 receptor immunoreactivity and receive direct contacts by orexin fibers (2003) Endocrinology, 144, pp. 1542-1548
• Ciriello, J., McMurray, J.C., Babic, T., de Oliveira, C.V., Collateral axonal projections from hypothalamic hypocretin neurons to cardiovascular sites in nucleus ambiguus and nucleus tractus solitarius (2003) Brain Res, 991, pp. 133-141
• Cluderay, J.E., Harrison, D.C., Hervieu, G.J., Protein distribution of the orexin-2 receptor in the rat central nervous system (2002) Regul Pept, 104, pp. 131-144
• Culler, M.D., Negro-Vilar, A., Endogenous inhibin suppresses only basal follicle-stimulating hormone secretion but suppresses all parameters of pulsatile luteinizing hormone secretion in the diestrus female rat (1989) Endocrinology, 124, pp. 2944-2953
• Cutler, D.J., Morris, R., Sheridhar, V., Wattam, T.A., Holmes, S., Patel, S., Arch, J.R., Williams, G., Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord (1999) Peptides, 20, pp. 1455-1470
• Date, Y., Mondal, M.S., Matsukura, S., Ueta, Y., Yamashita, H., Kaiya, H., Kangawa, K., Nakazato, M., Distribution of orexin/hypocretin in the rat median eminence and pituitary (2000) Brain Res Mol Brain Res, 76, pp. 1-6
• de Lecea, L., Kilduff, T.S., Peyron, C., Gao, X., Foye, P.E., Danielson, P.E., Fukuhara, C., Sutcliffe, J.G., The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity (1998) Proc Natl Acad Sci USA, 95, pp. 322-327
• de Lecea, L., Sutcliffe, J.G., Fabre, V., Hypocretins/orexins as integrators of physiological information: Lessons from mutant animals (2002) Neuropeptides, 36, pp. 85-95
• Dye, L., Blundell, J.E., Menstrual cycle and appetite control: Implications for weight regulation (1997) Hum Reprod, 12, pp. 1142-1151
• Ferguson, A.V., Samson, W.K., The orexin/hypocretin system: A critical regulator of neuroendocrine and autonomic function (2003) Front Neuroendocrinol, 24, pp. 141-150
• Furuta, M., Funabashi, T., Kimura, F., Suppressive action of orexin A on pulsatile luteinizing hormone secretion is potentiated by a low dose of estrogen in ovariectomized rats (2002) Neuroendocrinology, 75, pp. 151-157
• Garcia, M.C., Lopez, M., Gualillo, O., Seoane, L.M., Dieguez, C., Senaris, R.M., Hypothalamic levels of NPY, MCH, and prepro-orexin mRNA during pregnancy and lactation in the rat: Role of prolactin (2003) FASEB J, 17, pp. 1392-1400
• Geerling, J.C., Mettenleiter, T.C., Loewy, A.D., Orexin neurons project to diverse sympathetic outflow systems (2003) Neuroscience, 122, pp. 541-550
• Hara, J., Beuckmann, C.T., Nambu, T., Willie, J.T., Chemelli, R.M., Sinton, C.M., Sugiyama, F., Sakurai, T., Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity (2001) Neuron, 30, pp. 345-354
• Iqbal, J., Pompolo, S., Sakurai, T., Clarke, I.J., Evidence that orexin-containing neurones provide direct input to gonadotropin-releasing hormone neurones in the ovine hypothalamus (2001) J Neuroendocrinol, 13, pp. 1033-1041
• Irahara, M., Tamura, T., Matuzaki, T., Saito, S., Yasui, T., Yamano, S., Kamada, M., Aono, T., Orexin-A suppresses the pulsatile secretion of luteinizing hormone via beta-endorphin (2001) Biochem Biophys Res Commun, 281, pp. 232-236
• Irving, E.A., Harrison, D.C., Babbs, A.J., Mayes, A.C., Campbell, C.A., Hunter, A.J., Upton, N., Parsons, A.A., Increased cortical expression of the orexin-1 receptor following permanent middle cerebral artery occlusion in the rat (2002) Neurosci Lett, 324, pp. 53-56
• Johren, O., Bruggemann, N., Dendorfer, A., Dominiak, P., Gonadal steroids differentially regulate the messenger ribonucleic acid expression of pituitary orexin type 1 receptors and adrenal orexin type 2 receptors (2003) Endocrinology, 144, pp. 1219-1225
• Johren, O., Neidert, S.J., Kummer, M., Dendorfer, A., Dominiak, P., Preproorexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats (2001) Endocrinology, 142, pp. 3324-3331
• Kanenishi, K., Ueno, M., Momose, S., Kuwabara, H., Tanaka, H., Sato, C., Kobayashi, T., Hata, T., Prepro-orexin mRNA expression in the rat brain is increased during pregnancy (2004) Neurosci Lett, 368, pp. 73-77
• Karteris, E., Chen, J., Randeva, H.S., Expression of human prepro-orexin and signaling characteristics of orexin receptors in the male reproductive system (2004) J Clin Endocrinol Metab, 89, pp. 1957-1962
• Karteris, E., Machado, R.J., Chen, J., Zervou, S., Hillhouse, E.W., Randeva, H.S., Food deprivation differentially modulates orexin receptor expression and signaling in rat hypothalamus and adrenal cortex (2005) Am J Physiol Endocrinol Metab, 288, pp. E1089-E1100
• Karteris, E., Randeva, H.S., Grammatopoulos, D.K., Jaffe, R.B., Hillhouse, E.W., Expression and coupling characteristics of the CRH and orexin type 2 receptors in human fetal adrenals (2001) J Clin Endocrinol Metab, 86, pp. 4512-4519
• Kastin, A.J., Akerstrom, V., Orexin A but not orexin B rapidly enters brain from blood by simple diffusion (1999) J Pharmacol Exp Ther, 289, pp. 219-223
• Kohsaka, A., Watanobe, H., Kakizaki, Y., Suda, T., Schioth, H.B., A significant participation of orexin-A, a potent orexigenic peptide, in the preovulatory luteinizing hormone and prolactin surges in the rat (2001) Brain Res, 898, pp. 166-170
• Kok, S.W., Roelfsema, F., Overeem, S., Lammers, G.J., Frolich, M., Meinders, A.E., Pijl, H., Pulsatile LH release is diminished, whereas FSH secretion is normal, in hypocretin-deficient narcoleptic men (2004) Am J Physiol Endocrinol Metab, 287, pp. E630-E636
• Kukkonen, J.P., Holmqvist, T., Ammoun, S., Akerman, K.E., Functions of the orexinergic/hypocretinergic system (2002) Am J Physiol Cell Physiol, 283, pp. C1567-C1591
• Lang, M., Soll, R.M., Durrenberger, F., Dautzenberg, F.M., Beck-Sickinger, A.G., Structure-activity studies of orexin A and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands (2004) J Med Chem, 47, pp. 1153-1160
• Lin, J., Yan, G.T., Hao, X.H., Zhang, K., Wang, L.H., Xue, H., Establishment and primary application of a highly-sensitive orexin-A radioimmunoassay (2004) J Immunoassay Immunochem, 25, pp. 45-55
• McAtee, L.C., Sutton, S.W., Rudolph, D.A., Li, X., Aluisio, L.E., Phuong, V.K., Dvorak, C.A., Jones, T.K., Novel substituted 4-phenyl-[1,3]dioxanes: Potent and selective orexin receptor 2 (OX(2)R) antagonists (2004) Bioorg Med Chem Lett, 14, pp. 4225-4229
• Mieda, M., Yanagisawa, M., Sleep, feeding, and neuropeptides: Roles of orexins and orexin receptors (2002) Curr Opin Neurobiol, 12, pp. 339-345
• Nakabayashi, M., Suzuki, T., Takahashi, K., Totsune, K., Muramatsu, Y., Kaneko, C., Date, F., Sasano, H., Orexin-A expression in human peripheral tissues (2003) Mol Cell Endocrinol, 205, pp. 43-50
• Nambu, T., Sakurai, T., Mizukami, K., Hosoya, Y., Yanagisawa, M., Goto, K., Distribution of orexin neurons in the adult rat brain (1999) Brain Res, 827, pp. 243-260
• Nowak, K.W., Strowski, M.Z., Switonska, M.M., Kaczmarek, P., Singh, V., Fabis, M., Mackowiak, P., Malendowicz, L.K., Evidence that orexins A and B stimulate insulin secretion from rat pancreatic islets via both receptor subtypes (2005) Int J Mol Med, 15, pp. 969-972
• Olpe, H.R., Karlsson, G., Pozza, M.F., Brugger, F., Steinmann, M., van Riezen, H., Fagg, G., Bittiger, H., CGP 53348: A centrally active blocker of GABAB receptors (1990) Eur J Pharmacol, 187, pp. 27-38
• Parborell, F., Irusta, G., Vitale, A., Gonzalez, O., Pecci, A., Tesone, M., Gonadotropin-releasing hormone antagonist antide inhibits apoptosis of preovulatory follicle cells in rat ovary (2005) Biol Reprod, 72, pp. 659-666
• Peluffo, M.C., Bussmann, L., Stouffer, R.L., Tesone, M., Expression of caspase-2, -3, -8 and -9 proteins and enzyme activity in the corpus luteum of the rat at different stages during the natural estrous cycle (2006) Reproduction, 132, pp. 465-475
• Peyron, C., Tighe, D.K., van den Pol, A.N., de Lecea, L., Heller, H.C., Sutcliffe, J.G., Kilduff, T.S., Neurons containing hypocretin (orexin) project to multiple neuronal systems (1998) J Neurosci, 18, pp. 9996-10015
• Porkka-Heiskanen, T., Kalinchuk, A., Alanko, L., Huhtaniemi, I., Stenberg, D., Orexin A and B levels in the hypothalamus of female rats: The effects of the estrous cycle and age (2004) Eur J Endocrinol, 150, pp. 737-742
• Pu, S., Jain, M.R., Kalra, P.S., Kalra, S.P., Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (1998) Regul Pept, 78, pp. 133-136
• Randeva, H.S., Karteris, E., Grammatopoulos, D., Hillhouse, E.W., Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: Implications for adrenal function and energy homeostasis (2001) J Clin Endocrinol Metab, 86, pp. 4808-4813
• Russell, S.H., Small, C.J., Kennedy, A.R., Stanley, S.A., Seth, A., Murphy, K.G., Taheri, S., Bloom, S.R., Orexin A interactions in the hypothalamo-pituitary gonadal axis (2001) Endocrinology, 142, pp. 5294-5302
• Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R.M., Tanaka, H., Williams, S.C., Yanagisawa, M., Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior (1998) Cell, 92, pp. 573-585
• Sasson, R., Dearth, R.K., White, R.S., Chappell, P.E., Mellon, P.L., Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons (2006) Neuroendocrinology, 84, pp. 353-363
• Shirasaka, T., Nakazato, M., Matsukura, S., Takasaki, M., Kannan, H., Sympathetic and cardiovascular actions of orexins in conscious rats (1999) Am J Physiol Regul Integr Comp Physiol, 277, pp. R1780-R1785
• Silveyra, P., Catalano, P.N., Lux-Lantos, V., Libertun, C., Impact of proestrous milieu on expression of orexin receptors and prepro-orexin in rat hypothalamus and hypophysis: Actions of Cetrorelix and Nembutal (2007) Am J Physiol Endocrinol Metab, 292, pp. E820-E828
• Small, C.J., Goubillon, M.L., Murray, J.F., Siddiqui, A., Grimshaw, S.E., Young, H., Sivanesan, V., Wilson, C.A., Central orexin A has site-specific effects on luteinizing hormone release in female rats (2003) Endocrinology, 144, pp. 3225-3236
• Smart, D., Sabido-David, C., Brough, S.J., Jewitt, F., Johns, A., Porter, R.A., Jerman, J.C., SB-334867-A: The first selective orexin-1 receptor antagonist (2001) Br J Pharmacol, 132, pp. 1179-1182
• Takano, S., Kanai, S., Hosoya, H., Ohta, M., Uematsu, H., Miyasaka, K., Orexin-A does not stimulate food intake in old rats (2004) Am J Physiol Gastrointest Liver Physiol, 287, pp. G1182-G1187
• Tamura, T., Irahara, M., Tezuka, M., Kiyokawa, M., Aono, T., Orexins, orexigenic hypothalamic neuropeptides, suppress the pulsatile secretion of luteinizing hormone in ovariectomized female rats (1999) Biochem Biophys Res Commun, 264, pp. 759-762
• Tanida, M., Niijima, A., Shen, J., Yamada, S., Sawai, H., Fukuda, Y., Nagai, K., Dose-different effects of orexin-A on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats (2006) Exp Biol Med (Maywood), 231, pp. 1616-1625
• Trivedi, P., Yu, H., MacNeil, D.J., Van der Ploeg, L.H., Guan, X.M., Distribution of orexin receptor mRNA in the rat brain (1998) FEBS Lett, 438, pp. 71-75
• Wang, J.B., Murata, T., Narita, K., Honda, K., Higuchi, T., Variation in the expression of orexin and orexin receptors in the rat hypothalamus during the estrous cycle, pregnancy, parturition, and lactation (2003) Endocrine, 22, pp. 127-134
• Yasuda, T., Masaki, T., Kakuma, T., Hara, M., Nawata, T., Katsuragi, I., Yoshimatsu, H., Dual regulatory effects of orexins on sympathetic nerve activity innervating brown adipose tissue in rats (2005) Endocrinology, 146, pp. 2744-2748
• Yoshida, K., McCormack, S., Espana, R.A., Crocker, A., Scammell, T.E., Afferents to the orexin neurons of the rat brain (2006) J Comp Neurol, 494, pp. 845-861
• Zhang, W., Sakurai, T., Fukuda, Y., Kuwaki, T., Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice (2006) Am J Physiol Regul Integr Comp Physiol, 290, pp. R1654-R1663

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------