Abstract:
4‐|2‐(Dimethylamino)ethyl‐2‐14C| phenol (hordenine‐α‐14C) has been synthesised in three steps from |14C|potassium cyanide and p‐benzyloxybenzyl chloride which in turn was obtained in four steps from p‐hydroxybenzoic acid. Copyright © 1981 John Wiley & Sons, Ltd.
Registro:
Documento: |
Artículo
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Título: | Synthesis of 4‐|2‐(dimethylamino) ethyl‐2‐14C| phenol (hordenine‐α‐14C) |
Autor: | Russo, C.A.; Gros, E.G. |
Filiación: | Departamento de Quimica Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Buenos Aires, Argentina
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Palabras clave: | Hordenine‐α‐14C; Synthesis; Tyramine‐α‐14C; radioisotope; drug analysis; drug identification; drug synthesis; hordenine c 14; in vitro study; infrared spectrometry; mass spectrometry; preliminary communication; theoretical study; thin layer chromatography; tyramine c 14 |
Año: | 1981
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Volumen: | 18
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Número: | 8
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Página de inicio: | 1185
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Página de fin: | 1187
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DOI: |
http://dx.doi.org/10.1002/jlcr.2580180813 |
Título revista: | Journal of Labelled Compounds and Radiopharmaceuticals
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Título revista abreviado: | J. Label. Compd. Radiopharm.
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ISSN: | 03624803
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v18_n8_p1185_Russo |
Referencias:
- Matchett, T.J., Marion, L., Kirkwood, S., THE BIOGENESIS OF ALKALOIDS: VIII. THE ROLE OF METHIONINE IN THE FORMATION OF THE N-METHYL GROUPS OF THE ALKALOID HORDENINE (1953) Canadian Journal of Chemistry, 31, p. 488
- Rabitzsch, G., (1959) Planta Med., 7, p. 268
- Loev, B., Dawson, C.R., (1956) J. Am. Chem. Soc., 78, p. 6095
- Haslam, E., Haworth, R.D., Mills, S.D., Rogers, H.J., Armitage, R., Searle, R., (1961), p. 1836. , J. Chem. Soc; Shelton, R.S., van Camphen, N.G., Jr., Meiner, D.F., Poumerter, S.M., Andrews, E.R., Allen, R.E., Wyckoff, K.K., (1953) J. Am. Chem. Soc., 75, p. 5491
- (1963), p. 576. , Rabjohn N. (Editor) ‐ Organic Syntheses Coll. Vol. IV; Freidman, L., Shechter, H., Preparation of Nitriles from Halides and Sodium Cyanide. An Advantageous Nucleophilic Displacement in Dimethyl Sulfoxide1a (1960) The Journal of Organic Chemistry, 25, p. 877
- Benington, F., Morin, R.D., (1967) J. Org. Chem., 32, p. 1050
- Tomita, M., Nakaguchi, K., Tagaki, S., (1951) J. Pharm. Soc. Japan, 71, p. 1035
- Hauting, W., (1928) J. Am. Chem. Soc., 50, p. 3370
- (1955), p. 720. , Horning E.C. (Editor) ‐ Organic Syntheses Coll. Vol. III; Rosemund, K.W., Pfankuch, E., (1923) Ber., 56, p. 2258
- Bowman, R.E., Stroud, H.H., (1950), p. 1342. , J. Chem. Soc; Leete, E., Kirkwood, S., Marion, L., (1952) Can. J. Chem., 30, p. 754
- Digenis, G.A., Burkett, J.W., Mihranian, V., A convenient synthesis of 2 - [14C] - hordenine (1972) Journal of Labelled Compounds, 8, p. 231
- Ghosal, S., Srivastava, R., (1973) Phytochemistry, 12, p. 193
- (1975) Progress in Mass Spectrometry, 3. , Hesse M., Bernhard H. O., (Editors) ‐, Verlag Chemie
Citas:
---------- APA ----------
Russo, C.A. & Gros, E.G.
(1981)
. Synthesis of 4‐|2‐(dimethylamino) ethyl‐2‐14C| phenol (hordenine‐α‐14C). Journal of Labelled Compounds and Radiopharmaceuticals, 18(8), 1185-1187.
http://dx.doi.org/10.1002/jlcr.2580180813---------- CHICAGO ----------
Russo, C.A., Gros, E.G.
"Synthesis of 4‐|2‐(dimethylamino) ethyl‐2‐14C| phenol (hordenine‐α‐14C)"
. Journal of Labelled Compounds and Radiopharmaceuticals 18, no. 8
(1981) : 1185-1187.
http://dx.doi.org/10.1002/jlcr.2580180813---------- MLA ----------
Russo, C.A., Gros, E.G.
"Synthesis of 4‐|2‐(dimethylamino) ethyl‐2‐14C| phenol (hordenine‐α‐14C)"
. Journal of Labelled Compounds and Radiopharmaceuticals, vol. 18, no. 8, 1981, pp. 1185-1187.
http://dx.doi.org/10.1002/jlcr.2580180813---------- VANCOUVER ----------
Russo, C.A., Gros, E.G. Synthesis of 4‐|2‐(dimethylamino) ethyl‐2‐14C| phenol (hordenine‐α‐14C). J. Label. Compd. Radiopharm. 1981;18(8):1185-1187.
http://dx.doi.org/10.1002/jlcr.2580180813