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drug mechanism
168
"A Minimalist Approach to the Design of Complexity-Enriched Bioactive Small Molecules: Discovery of Phenanthrenoid Mimics as Antiproliferative Agents"
(2018) Alonso, F.;Quezada, M.J.;Gola, G.F. (
...
)Ramírez, J.A. ChemMedChem. 13(16):1732-1740
"Determining the virus life-cycle stage blocked by an antiviral"
(2018) Sepúlveda, C.S.; García, C.C.; Damonte, E.B. Methods in Molecular Biology. 1604:371-392
"Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis article"
(2018) Gueron, G.;Anselmino, N.;Chiarella, P. (
...
)Vazquez, E. Cell Death and Disease. 9(2)
"The interplay between viperin antiviral activity, lipid droplets and Junín mammarenavirus multiplication"
(2018) Peña Cárcamo, J.R.;Morell, M.L.;Vázquez, C.A. (
...
)García, C.C. Virology. 514:216-229
"Antiviral activity of A771726, the active metabolite of leflunomide, against Junín virus"
(2018) Sepúlveda, C.S.; García, C.C.; Damonte, E.B. Journal of Medical Virology. 90(5):819-827
"Metallated porphyrin-doped conjugated polymer nanoparticles for efficient photodynamic therapy of brain and colorectal tumor cells"
(2018) Ibarra, L.E.;Porcal, G.V.;Macor, L.P. (
...
)Palacios, R.E. Nanomedicine. 13(6):605-624
"Evaluation of nitroxyl donors’ effect on mycobacteria"
(2018) Galizia, J.;Acosta, M.P.;Urdániz, E. (
...
)Piuri, M. Tuberculosis. 109:35-40
"Chronic pregabalin treatment decreases excitability of dentate gyrus and accelerates maturation of adult-born granule cells"
(2017) Lempel, A.A.;Coll, L.;Schinder, A.F. (
...
)Piriz, J. Journal of Neurochemistry. 140(2):257-267
"Cooperative behavior of fluoroquinolone combinations against Escherichia coli and Staphylococcus aureus"
(2017) Vitorino, G.P.;Becerra, M.C.;Barrera, G.D. (
...
)Mazzieri, M.R. Biological and Pharmaceutical Bulletin. 40(6):758-764
"Activated by evoked released protons modulate synaptic transmission at the mouse calyx of held synapse"
(2017) González-Inchauspe, C.; Urbano, F.J.; Di Guilmi, M.N.; Uchitel, O.D. Journal of Neuroscience. 37(10):2589-2599
"Synthesis and antifungal activity of bile acid-derived oxazoles"
(2016) Fernández, L.R.;Svetaz, L.;Butassi, E. (
...
)Sánchez, M. Steroids. 108:68-76
"Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase"
(2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Drug Discovery. 11(3):307-320
"Local administration of platelet-derived growth factor B (PDGFB) improves follicular development and ovarian angiogenesis in a rat model of Polycystic Ovary Syndrome"
(2016) Di Pietro, M.;Scotti, L.;Irusta, G. (
...
)Abramovich, D. Molecular and Cellular Endocrinology. 433:47-55
"Cognitive enhancers versus addictive psychostimulants: The good and bad side of dopamine on prefrontal cortical circuits"
(2016) Bisagno, V.; González, B.; Urbano, F.J. Pharmacological Research. 109:108-118
"Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549"
(2015) Marostica, L.L.;Silva, I.T.;Kratz, J.M. (
...
)Simões, C.M.O. Chemical Research in Toxicology. 28(10):1949-1960
"Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation"
(2015) Ahmad, S.;Hewett, P.W.;Fujisawa, T. (
...
)Ahmed, A. Thrombosis and Haemostasis. 113(2):329-337
"Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1"
(2015) Diogo, J.V.;Novo, S.G.;González, M.J. (
...
)Bratanich, A.C. Research in Veterinary Science. 98:142-144
"Antiviral activity of an N-allyl acridone against dengue virus"
(2015) Mazzucco, M.B.;Talarico, L.B.;Vatansever, S. (
...
)Damonte, E.B. Journal of Biomedical Science. 22(1)
"Effect of different terpene-containing essential oils on the proliferation of echinococcus granulosus larval cells"
(2014) Albani, C.M.; Denegri, G.M.; Elissondo, M.C. Interdisciplinary Perspectives on Infectious Diseases. 2014
"N-nitrosomelatonin enhances photic synchronization of mammalian circadian rhythms"
(2014) Baidanoff, F.M.;Plano, S.A.;Doctorovich, F. (
...
)Chiesa, J.J. Journal of Neurochemistry. 129(1):60-71
"The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice"
(2014) Meyer, M.;Gonzalez Deniselle, M.C.;Hunt, H. (
...
)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 143:40-48
"Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin"
(2014) Quintana, V.M.;Torres, N.I.;Wachsman, M.B. (
...
)Chikindas, M. Journal of Applied Microbiology. 117(5):1253-1259
"Naturally occurring compounds elicit hiv-1 replication in chronically infected promonocytic cells"
(2014) Barquero, A.A.;Dávola, M.E.;Riva, D.A. (
...
)Alché, L.E. BioMed Research International. 2014
"Progesterone reduces secondary damage, preserves white matter, and improves locomotor outcome after spinal cord contusion"
(2014) Garcia-Ovejero, D.;González, S.;Paniagua-Torija, B. (
...
)Labombarda, F. Journal of Neurotrauma. 31(9):857-871
"Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor"
(2013) Rey, M.;Kruse, M.S.;Alvarez, L.D. (
...
)Coirini, H. Experimental Neurology. 249:49-58
"Positive modulation of the α9α10 nicotinic cholinergic receptor by ascorbic acid"
(2013) Boffi, J.C.;Wedemeyer, C.;Lipovsek, M. (
...
)Elgoyhen, A.B. British Journal of Pharmacology. 168(4):954-965
"Acridones as antiviral agents: Synthesis, chemical and biological properties"
(2013) Sepúlveda, C.S.;Fascio, M.L.;García, C.C. (
...
)Damonte, E.B. Current Medicinal Chemistry. 20(19):2402-2414
"Acute effects of pregabalin on the function and cellular distribution of CaV2.1 in HEK293t cells"
(2013) Weissmann, C.; Di Guilmi, M.N.; Urbano, F.J.; Uchitel, O.D. Brain Research Bulletin. 90(1):107-113
"Anticoagulant activity of a unique sulfated pyranosic (1→3)-β-L- arabinan through direct interaction with thrombin"
(2013) Fernández, P.V.;Quintana, I.;Cerezo, A.S. (
...
)Ciancia, M. Journal of Biological Chemistry. 288(1):223-233
"N-Acetylcysteine affects obesity-related protein expression in 3T3-L1 adipocytes"
(2013) Calzadilla, P.;Gómez-Serrano, M.;García-Santos, E. (
...
)Guerra, L.N. Redox Report. 18(6):210-218
"Is vernakalant better or not compared with other treatments for conversion acute atrial fibrillation?"
(2013) Conde, D. International Journal of Cardiology. 169(2):95-96
"Enhancing a declarative memory in humans: The effect of clonazepam on reconsolidation"
(2013) Rodríguez, M.L.C.;Campos, J.;Forcato, C. (
...
)Pedreira, M.E. Neuropharmacology. 64:432-442
"Proliferative inhibition and apoptotic mechanism on human non-small-cell lung cancer (A549 cells) of a novel cucurbitacin from Wilbrandia ebracteata cogn"
(2013) Silva, I.T.;Teixeira, C.R.;Lang, K.L. (
...
)Simões, C.M.O. International Journal of Cancer Research. 9(2):54-68
"Isolation of three new ent-labdane diterpenes from Dodonaea viscosa Jacquin (Sapindaceae): Preliminary evaluation of antiherpes activity"
(2012) Oliveira, S.Q.D.;Almeida, M.T.R.D.;Maraslis, F. (
...
)Schenkel, E.P. Phytochemistry Letters. 5(3):500-505
"System among the corticosteroids: Specificity and molecular dynamics"
(2012) Brookes, J.C.;Galigniana, M.D.;Harker, A.H. (
...
)Vinson, G.P. Journal of the Royal Society Interface. 9(66):43-53
"DHEA inhibits measles virus through a mechanism independent of its ability to modulate the Raf/MEK/ERK signaling pathway"
(2012) Torres, N.I.; Castilla, V.; Wachsman, M. Future Virology. 7(11):1115-1125
"Antiparasitic effect of vitamin B12 on Trypanosoma cruzi"
(2012) Ciccarelli, A.B.;Frank, F.M.;Puente, V. (
...
)Lombardo, M.E. Antimicrobial Agents and Chemotherapy. 56(10):5315-5320
"New antibacterials for the treatment of toxoplasmosis; A patent review"
(2012) Rodriguez, J.B.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 22(3):311-333
"Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis"
(2012) Garay, L.I.;González Deniselle, M.C.;Brocca, M.E. (
...
)De Nicola, A.F. Neuroscience. 226:40-50
"Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells"
(2012) Montesinos, M.M.;Alamino, V.A.;Mascanfroni, I.D. (
...
)Pellizas, C.G. Steroids. 77(1-2):67-76
"2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase"
(2012) Rodrígues-Poveda, C.A.; González-Pacanowska, D.; Szajnman, S.H.; Rodríguez, J.B. Antimicrobial Agents and Chemotherapy. 56(8):4483-4486
"Steroid receptor coupling becomes nuclear"
(2012) Galigniana, M.D. Chemistry and Biology. 19(6):662-663
"Effect of SOM230 (Pasireotide) on corticotropic cells: Action in dogs with Cushing's disease"
(2011) Castillo, V.;Theodoropoulou, M.;Stalla, J. (
...
)Arzt, E. Neuroendocrinology. 94(2):124-136
"Daily treatment with α-naphthoflavone enhances follicular growth and ovulation rate in the rat"
(2011) Barreiro, K.A.;Di Yorio, M.P.;Artillo-Guida, R.D. (
...
)Faletti, A.G. Toxicology and Applied Pharmacology. 252(1):11-17
"Administration of a gonadotropin-releasing hormone agonist affects corpus luteum vascular stability and development and induces luteal apoptosis in a rat model of ovarian hyperstimulation syndrome"
(2011) Scotti, L.;Irusta, G.;Abramovich, D. (
...
)Parborell, F. Molecular and Cellular Endocrinology. 335(2):116-125
"Increased aromatase expression in the hippocampus of spontaneously hypertensive rats: Effects of estradiol administration"
(2011) Pietranera, L.;Bellini, M.J.;Arévalo, M.A. (
...
)De Nicola, A.F. Neuroscience. 174:151-159
"Pituitary tumors: Cell type-specific roles for BMP-4"
(2010) Labeur, M.;Páez-Pereda, M.;Haedo, M. (
...
)Stalla, G.K. Molecular and Cellular Endocrinology. 326(1-2):85-88
"Synthesis and biological evaluation of N-thia-carba-thymidine as an antiherpetic agent"
(2010) Elhalem, E.; Pujol, C.A.; Damonte, E.B.; Rodriguez, J.B. Tetrahedron. 66(18):3332-3340
"Molecular mechanisms of glucocorticoids action: From basic research to clinical implications"
(2010) Liberman, A.C.;Castro, C.N.;Noguerol, M.A. (
...
)Arzt, E. Current Immunology Reviews. 6(4):371-380
"Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids"
(2010) Presman, D.M.;Alvarez, L.D.;Levi, V. (
...
)Pecci, A. PLoS ONE. 5(10)
"Anti-adenovirus activity of epiandrosterone and dehydroepiandrosterone derivatives"
(2010) Romanutti, C.;Bruttomesso, A.C.;Castilla, V. (
...
)Wachsman, M.B. Chemotherapy. 56(2):158-165
"Effects of T-type calcium channel blockers on cocaine-induced hyperlocomotion and thalamocortical GABAergic abnormalities in mice"
(2010) Bisagno, V.;Raineri, M.;Peskin, V. (
...
)Urbano, F.J. Psychopharmacology. 212(2):205-214
"Disruption of the dopamine D2 receptor impairs insulin secretion and causes glucose intolerance"
(2010) García-Tornadú, I.;Ornstein, A.M.;Chamson-Reig, A. (
...
)Becu-Villalobos, D. Endocrinology. 151(4):1441-1450
"Overview of anticoagulant activity of sulfated polysaccharides from seaweeds in relation to their structures, focusing on those of green seaweeds"
(2010) Ciancia, M.; Quintana, I.; Cerezo, A.S. Current Medicinal Chemistry. 17(23):2503-2529
"Structure of the glucocorticoid receptor, a flexible protein that can adapt to different ligands"
(2010) Veleiro, A.S.; Alvarez, L.D.; Eduardo, S.L.; Burton, G. ChemMedChem. 5(5):649-659
"Inhibitory effect of quercetin on matrix metalloproteinase 9 activity Molecular mechanism and structure-activity relationship of the flavonoid-enzyme interaction"
(2010) Saragusti, A.C.;Ortega, M.G.;Cabrera, J.L. (
...
)Chiabrando, G.A. European Journal of Pharmacology. 644(1-3):138-145
"Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas"
(2009) Labeur, M.; Paez-Pereda, M.; Arzt, E.; Stalla, G.K. Reviews in Endocrine and Metabolic Disorders. 10(2):103-109
"Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration"
(2009) De Nicola, A.F.;Labombarda, F.;Deniselle, M.C.G. (
...
)Schumacher, M. Frontiers in Neuroendocrinology. 30(2):173-187
"Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog"
(2009) Careaga, V.P.;Bueno, C.;Muniain, C. (
...
)Maier, M.S. Chemotherapy. 55(1):60-68
"Emerging pharmacotherapy of tinnitus"
(2009) Langguth, B.; Salvi, R.; Elgoyhen, A.B. Expert Opinion on Emerging Drugs. 14(4):687-702
"Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms"
(2009) Frick, L.R.; Rapanelli, M.; Cremaschi, G.A.; Genaro, A.M. Brain, Behavior, and Immunity. 23(1):36-40
"Glutamatergic system: Another target for the action of porphyrinogenic agents"
(2009) Lavandera, J.V.;Fossati, M.;Azcurra, J. (
...
)Buzaleh, A.M. Cellular and Molecular Biology. 55(1):23-28
"Induction of hepatic aminolevulinate acid synthetase activity by isoflurane in a genetic model for erythropoietic protoporphyria"
(2009) Buzaleh, A.M.;Morán-Jiménez, M.J.;García-Bravo, M. (
...
)Fontanellas, A. Cellular and Molecular Biology. 55(1):38-44
"Alpha9 nicotinic acetylcholine receptors and the treatment of pain"
(2009) McIntosh, J.M.;Absalom, N.;Chebib, M. (
...
)Vincler, M. Biochemical Pharmacology. 78(7):693-702
"Effects of Progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury"
(2009) Labombarda, F.;González, S.L.;Lima, A. (
...
)De Nicola, A.F. GLIA. 57(8):884-897
"In vitro antiviral activity of dehydroepiandrosterone and its synthetic derivatives against vesicular stomatitis virus"
(2009) Romanutti, C.;Bruttomesso, A.C.;Castilla, V. (
...
)Wachsman, M.B. Veterinary Journal. 182(2):327-335
"In vitro effect of a new cinnamic acid derivative against the epimastigote form of Trypanosoma cruzi"
(2009) Andreu, G.L.P.;Inada, N.M.;Pellón, R.F. (
...
)Vercesi, A.E. Arzneimittel-Forschung/Drug Research. 59(4):207-211
"Molecular mechanisms of action of some immunosuppresive drugs "
(2008) Liberman, A.C.; Druker, J.; Refojo, D.; Arzt, E. Medicina. 68(6):455-464
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase"
(2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (
...
)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Exploring the molecular basis of action of the passive antiglucocorticoid 21-hydroxy-6,19-epoxyprogesterone"
(2008) Álvarez, L.D.;Martí, M.A.;Veleiro, A.S. (
...
)Burton, G. Journal of Medicinal Chemistry. 51(5):1352-1360
"Dehydroepiandrosterone and metformin modulate progesterone-induced blocking factor (PIBF), cyclooxygenase 2 (COX2) and cytokines in early pregnant mice"
(2008) Luchetti, C.G.;Mikó, E.;Szekeres-Bartho, J. (
...
)Motta, A.B. Journal of Steroid Biochemistry and Molecular Biology. 111(3-5):200-207
"New acridinone derivative with trypanocidal activity"
(2008) Pardo Andreu, G.L.;Inada, N.M.;Pellón, R.F. (
...
)Vercesi, A.E. International Journal of Antimicrobial Agents. 31(5):502-504
"Inhibition of cyclooxygenase-2 (COX-2) by meloxicam decreases the incidence of ovarian hyperstimulation syndrome in a rat model"
(2008) Quintana, R.;Kopcow, L.;Marconi, G. (
...
)Paz, D.A. Fertility and Sterility. 90(4 SUPPL):1511-1516
"VIP limits LPS-induced nitric oxide production through IL-10 in NOD mice macrophages"
(2007) Larocca, L.;Calafat, M.;Roca, V. (
...
)Leirós, C.P. International Immunopharmacology. 7(10):1343-1349
"Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment"
(2007) Croci, D.O.;Zacarías Fluck, M.F.;Rico, M.J. (
...
)Scharovsky, O.G. Cancer Immunology, Immunotherapy. 56(11):1687-1700
"Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica"
(2007) Mandal, P.;Mateu, C.G.;Chattopadhyay, K. (
...
)Ray, B. Antiviral Chemistry and Chemotherapy. 18(3):153-162
"Leptin promotes cell proliferation and survival of trophoblastic cells"
(2007) Magariños, M.P.;Sánchez-Margalet, V.;Kotler, M. (
...
)Varone, C.L. Biology of Reproduction. 76(2):203-210
"Cardiovascular effects of tibolone: A selective tissue estrogenic activity regulator"
(2007) Campisi, R.; Marengo, F.D. Cardiovascular Drug Reviews. 25(2):132-145
"Trypanosoma cruzi: In vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg)"
(2007) Güida, M.C.;Esteva, M.I.;Camino, A. (
...
)Paveto, C. Experimental Parasitology. 117(2):188-194
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases"
(2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"Melatonin inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes"
(2006) Presman, D.M.;Hoijman, E.;Ceballos, N.R. (
...
)Pecci, A. Endocrinology. 147(11):5452-5459
"Naturally-occurring cyclopeptides: Structures and bioactivity"
(2006) Pomilio, A.B.; Battista, M.E.; Vitale, A.A. Current Organic Chemistry. 10(16):2075-2121
"Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition"
(2006) Moreno, S.; Scheyer, T.; Romano, C.S.; Vojnov, A.A. Free Radical Research. 40(2):223-231
"Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats"
(2006) Abramovich, D.; Parborell, F.; Tesone, M. Biology of Reproduction. 75(3):434-441
"Antiviral activity of a carrageenan from Gigartina skottsbergii against intraperitoneal murine herpes simplex virus infection"
(2006) Pujol, C.A.;Scolaro, L.A.;Ciancia, M. (
...
)Damonte, E.B. Planta Medica. 72(2):121-125
"VIP and tolerance induction in autoimmunity"
(2006) Rosignoli, F.;Torroba, M.;Juarranz, Y. (
...
)Leceta, J. Annals of the New York Academy of Sciences. 1070:525-530
"Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease"
(2005) Gonzalez Deniselle, M.C.;Garay, L.;Gonzalez, S. (
...
)De Nicola, A.F. Experimental Neurology. 195(2):518-523
"Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons"
(2005) Gonzalez, S.L.;Labombarda, F.;Gonzalez Deniselle, M.C. (
...
)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 94(1-3 SPEC ISS):143-149
"An antibacterial and antiviral peptide produced by Enterococcus mundtii ST4V isolated from soya beans"
(2005) Todorov, S.D.;Wachsman, M.B.;Knoetze, H. (
...
)Dicks, L.M.T. International Journal of Antimicrobial Agents. 25(6):508-513
"Antiviral mode of action of a synthetic brassinosteroid against Junin virus replication"
(2005) Castilla, V.;Larzábal, M.;Sgalippa, N.A. (
...
)Coto, C.E. Antiviral Research. 68(2):88-95
"Mixtures of natural and synthetic antifungal agents"
(2005) López-Malo, A.; Palou, E.; León-Cruz, R.; Alzamora, S.M. Advances in Experimental Medicine and Biology. 571:261-286
"Sensitivity to ALA-PDT of cell lines with different nitric oxide production and resistance to NO cytotoxicity"
(2005) Di Venosa, G.;Perotti, C.;Fukuda, H. (
...
)Casas, A. Journal of Photochemistry and Photobiology B: Biology. 80(3):195-202
"Anti-herpes simplex virus activity of sulfated galactans from the red seaweeds Gymnogongrus griffithsiae and Cryptonemia crenulata"
(2004) Talarico, L.B.;Zibetti, R.G.M.;Faria, P.C.S. (
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)Damonte, E.B. International Journal of Biological Macromolecules. 34(1-2):63-71
"Oestradiol restores cell proliferation in dentate gyrus and subventricular zone of streptozotocin-diabetic mice"
(2004) Saravia, F.;Revsin, Y.;Lux-Lantos, V. (
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)De Nicola, A.F. Journal of Neuroendocrinology. 16(8):704-710
"Sulfated seaweed polysaccharides as antiviral agents"
(2004) Damonte, E.B.; Matulewicz, M.C.; Cerezo, A.S. Current Medicinal Chemistry. 11(18):2399-2419
"Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA ρ1 receptor"
(2004) Goutman, J.D.; Calvo, D.J. British Journal of Pharmacology. 141(4):717-727
"Antiherpetic mode of action of (22S,23S)-3β-bromo-5α,22,23- trihydroxystigmastan-6-one in vitro"
(2004) Wachsman, M.B.;Castilla, V.;Talarico, L.B. (
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)Coto, C.E. International Journal of Antimicrobial Agents. 23(5):524-526
"Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleptides to type I insulin-like growth factor receptor rnRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity"
(2004) Salatino, M.;Schillaci, R.;Proietti, C.J. (
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)Elizalde, P.V. Oncogene. 23(30):5161-5174
"Protective effect of a natural carrageenan on genital herpes simplex virus infection in mice"
(2004) Carlucci, M.J.;Scolaro, L.A.;Noseda, M.D. (
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)Damonte, E.B. Antiviral Research. 64(2):137-141
"Anti-Trypanosoma cruzi Activity of Green Tea (Camellia sinensis) Catechins"
(2004) Paveto, C.;Güida, M.C.;Esteva, M.I. (
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)Torres, H.N. Antimicrobial Agents and Chemotherapy. 48(1):69-74
"Meridianins, a new family of protein kinase inhibitors isolated from the Ascidian Aplidium meridianum"
(2004) Gompel, M.;Leost, M.;Bal De Kier Joffe, E. (
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)Meijer, L. Bioorganic and Medicinal Chemistry Letters. 14(7):1703-1707
"Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein"
(2004) Fitzsimons, C.P.;Monczor, F.;Fernández, N. (
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)Davio, C. Journal of Biological Chemistry. 279(33):34431-34439
"Immunostimulatory effects of plasmid DNA and synthetic oligodeoxynucleotides"
(2003) Zelenay, S.; Elías, F.; Fló, J. European Journal of Immunology. 33(5):1382-1392
"Nifedipine-mediated mobilization of intracellular calcium stores increases spontaneous neurotransmitter release at neonatal rat motor nerve terminals"
(2003) Piriz, J.; Siri, M.D.R.; Pagani, R.; Uchitel, O.D. Journal of Pharmacology and Experimental Therapeutics. 306(2):658-663
"Flavonoid modulation of ionic currents mediated by GABAA and GABAC receptors"
(2003) Goutman, J.D.;Waxemberg, M.D.;Doñate-Oliver, F. (
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)Calvo, D.J. European Journal of Pharmacology. 461(2-3):79-87
"Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease"
(2003) Urbina, J.A.;Concepcion, J.L.;Montalvetti, A. (
...
)Docampo, R. Antimicrobial Agents and Chemotherapy. 47(6):2047-2050
"Differential inhibitory action of two azoic compounds against arenaviruses"
(2003) García, C.C.; Candurra, N.A.; Damonte, E.B. International Journal of Antimicrobial Agents. 21(4):319-324
"A comparative study of the photophysical and phototoxic properties of octakis(decyloxy)phthalocyaninato zinc(II), incorporated in a hydrophilic polymer, in liposomes and in non-ionic micelles"
(2003) Rodriguez, M.E.;Morán, F.;Bonansea, A. (
...
)Dicelio, L.E. Photochemical and Photobiological Sciences. 2(10):988-994
"Pharmacophoric pattern of anti-epileptic sulfonamides and sulfamates. Theoretical study of the associated requirements"
(2002) Barrios, I.A; Bruno-Blanch, L.E; Estiú, G.L Journal of Molecular Structure: THEOCHEM. 580(1-3):243-250
"Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum"
(2002) De Macedo, C.S.; Uhrig, M.L.; Kimura, E.A.; Katzin, A.M. FEMS Microbiology Letters. 207(1):13-20
"Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland"
(2002) Rosignoli, F.; Pérez Leirós, C. European Journal of Pharmacology. 439(1-3):27-33
"An antiviral principle present in a purified fraction from Melia azedarach L. leaf aqueous extract restrains herpes simplex virus type 1 propagation"
(2002) Alché, L.E.; Barquero, A.A.; Sanjuan, N.A.; Coto, C.E. Phytotherapy Research. 16(4):348-352
"Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus"
(2002) Pujol, C.A.;Estevez, J.M.;Carlucci, M.J. (
...
)Damonte, E.B. Antiviral Chemistry and Chemotherapy. 13(2):83-89
"Correlation between pregnanesteroid conformation, receptor affinity, and anti-natriuretic effect"
(2002) Piwien-Pilipuk, G.; Kanelakis, K.C.; Galigniana, M.D. European Journal of Pharmacology. 454(2-3):131-143
"Effective treatment of mouse herpetic stromal keratitis with meliacine, a plant-derived antiviral"
(2001) Alché, L.E.; Berra, A.; Coto, C.E. International Antiviral News. 9(8):132-135
"Pharmacophore model for antiepileptic drugs acting on sodium channels"
(2001) Tasso, S.M.; Bruno-Blanch, L.E.; Estiú, G.L. Journal of Molecular Modeling. 7(7):231-239
"Preparation and cytotoxicity toward cancer cells of mono(arylimino) derivatives of β-lapachone"
(2001) Di Chenna, P.H.;Benedetti-Doctorovich, V.;Baggio, R.F. (
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)Burton, G. Journal of Medicinal Chemistry. 44(15):2486-2489
"Dissimilar behavior of lymph cells in response to the action of aluminum. In vitro and in vivo studies"
(2001) Lauricella, A.M.; Garbossa, G.; Nesse, A. International Immunopharmacology. 1(9-10):1725-1732
"Changes in fos expression in various brain regions during deoxycorticosterone acetate treatment: Relation to salt appetite, vasopressin mRNA and the mineralocorticoid receptor"
(2001) Pietranera, L.;Saravia, F.E.;Mcewen, B.S. (
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)De Nicola, A.F. Neuroendocrinology. 74(6):396-406
"Administration of volatile anaesthetics to animals treated with cobalt as inductor of heme oxygenase"
(2000) Buzaleh, A.M.; Del Carmen Batlle, A.M. Pharmacology Reviews and Communications. 11(1):39-47
"Mechanism of action of the potent sodium-retaining steroid 11,19- oxidoprogesterone"
(2000) Galigniana, M.D.;Vicent, G.P.;Piwien-Pilipuk, G. (
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)Lantos, C.P. Molecular Pharmacology. 58(1):58-70
"The influence of the vehicle on the synthesis of porphyrins after topical application of 5-aminolaevulinic acid. Implications in cutaneous photodynamic sensitization"
(2000) Casas, A.; Fukuda, H.; Di Venosa, G.; Del C.Batlle, A.M. British Journal of Dermatology. 143(3):564-572
"Nerve growth factor and retinoic acid inhibit proliferation and invasion in thyroid tumor cells"
(2000) Páez Pereda, M.;Missale, C.;Grübler, Y. (
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)Stalla, G.K. Molecular and Cellular Endocrinology. 167(1-2):99-106
"The dopamine D 2 , but not D 3 or D 4 , receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice"
(1999) Ralph, R.J.;Varty, G.B.;Kelly, M.A. (
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)Geyer, M.A. Journal of Neuroscience. 19(11):4627-4633
"Effect of crude extracts from melia azedarach L. on the multiplication of chlamydias in different cellular systems "
(1999) Venier, M.;Wachsman, M.;Rodriguez Fermepin, M. (
...
)De Torres, R. Revista Argentina de Microbiologia. 31(SUPPL 1):24-26
"Glucocorticoid regulation of motoneuronal parameters in rats with spinal cord injury"
(1999) Gonzalez, S.L.;Saravia, F.;Gonzalez Deniselle, M.C. (
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)De Nicola, A.F. Cellular and Molecular Neurobiology. 19(5):597-611
"Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi"
(1998) Rodriguez, J.B.;Zhong, L.;Docampo, R. (
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)Gros, E.G. Bioorganic and Medicinal Chemistry Letters. 8(22):3257-3260
"Evaluation of the porphyrinogenic risk of antineoplastics"
(1997) Cochón, A.C.; Aldonatti, C.; San Martín De Viale, L.C.; De Calmanovici, R.W. Journal of Applied Toxicology. 17(3):171-177
"Enhancement of aminolevulinic acid based photodynamic therapy by adriamycin"
(1997) Casas, A.; Fukuda, H.; Riley, P.; Del C. Batlle, A.M. Cancer Letters. 121(1):105-113
"Antiherpetic activity of S1, an algal derived sulphated galactan"
(1996) Pujol, C.A.; Errea, M.I.; Matulewicz, M.C.; Damonte, E.B. Phytotherapy Research. 10(5):410-413
"Liver ferrochelatase from normal and hexachlorobenzene porphyric rats. mechanism of drug action"
(1991) Ríos De Molina, M.D.C.; De Catabbi, S.B.; De Viale, L.C.S.M. International Journal of Biochemistry. 23(7-8):669-673
"Induction of a refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L"
(1988) Andrei, G.M.; Damonte, E.B.; de Torres, R.A.; Coto, C.E. Antiviral Research. 9(4):221-231
"Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation?"
(1987) Viggiano, M.;Franchi, A.M.;Dveksler, G. (
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)Gimeno, A.L. Prostaglandins, Leukotrienes and Medicine. 28(3):285-302
"The effect of griseofulvin on the heme pathway. Studies on tissue explant cultures"
(1987) Vasquez, E.;Afonso, S.;Buzaleh, A.M. (
...
)Batlle, A. Toxicology. 46(1):73-82
"Diabetes alters the reactivity of myocardium to a thromboxane analogue"
(1987) Canga, L.; Gorelik, G.; Sterin-Borda, L. Canadian Journal of Physiology and Pharmacology. 65(4):499-503
"Uptake and release of 3H prostaglandins E2 and F2α in uterin strips isolated from ovariectomized rats. Influence of in vitro progesterone"
(1987) Gimeno, M.F.; Franchi, A.M.; González, E.T.; Gimeno, A.L. Prostaglandins. 33(1):51-61
"Effect of GABA and benzodiazepines on testicular androgen production"
(1987) Ritta, M.N.; Campos, M.B.; Calandra, R.S. Life Sciences. 40(8):791-798
"13-cis-Retinal stimulates proliferation and induces intranuclear protein accumulation in the human mammary tumor cells MCF-7"
(1987) Resnicoff, M.; Medrano, E.E. Biochemical and Biophysical Research Communications. 143(1):309-315
"Effect of corticosteroids on proximal tubular acidification in the rat"
(1987) Damasco, M.C.; Malnic, G. Mineral and Electrolyte Metabolism. 13(1):26-32
"Antiviral effects of Melia azedarach L. leaves extracts on Sindbis virus-infected cells"
(1987) Wachsman, M.B.; Damonte, E.B.; Coto, C.E.; De Torres, R.A. Antiviral Research. 8(1):1-12
"Regulation by insulin of cyclic nucleotide phosphodiesterase (PDE) from rat luteal cells"
(1987) Téllez-Iñón, M.T.;Ladenheim, R.G.;Ulloa, R. (
...
)Tesone, M. Hormone and Metabolic Research. 19(6):249-252
"About phototoxicity of griseofulvin. Possible mechanisms of action using cultures of tissular explants"
(1987) Afonso, S.;Buzaleh, A.M.;Navone, N. (
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)Del Batille, C.A.M. Revista Argentina de Dermatologia. 68(5):303-310
"S-adenosyl-L-methionine, a mechanism for its action of lead mobilization and disposal in lead poisoning"
(1986) Del Batlle, C.A.M.; Paredes, S.R.; Fukuda, H. Biochemical Archives. 2(4):293-303
"Mechanism of the inhibitory effect of 11 β-hydroxypregna-1,4-diene-3,20-dione (ΔHOP) at high concentrations in RNA synthesis"
(1986) Gonzalez, M.D.;Rondinone, C.M.;Burton, G. (
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)Roldán, A. Acta Physiologica et Pharmacologica Latinoamericana. 36(3):303-312
"Androgen metabolism in the human epididymis. effect of in vivo estrogen administration"
(1986) Vazquez, M.H.;de Larminat, M.-A.;Gurpide, E. (
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)Blaquier, J.A. Journal of Steroid Biochemistry. 25(2):239-244
"Changes in growth hormone and prolactin release after superior cervical ganglionectomy of rats"
(1986) Cardinali, D.P.; Boado, R.J.; Vacas, M.I.; Deza, S. Brain Research. 363(2):350-353
"ᵦ-(-4 Chlorophenyl) GABA (Baclofen) Inhibits Prolactin and Thyrotropin Release by Acting on the Rat Brain"
(1986) Lux, V.A.R.; Somoza, G.M.; Libertun, C. Proceedings of the Society for Experimental Biology and Medicine. 183(3):358-362
"Modification of sarcolemmal enzymes by chagasic IgG and its effect of cardiac contractility"
(1986) Pascual, J.;Borda, E.;Cossio, P. (
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)Sterin-Borda, L. Biochemical Pharmacology. 35(21):3839-3845
"H-2 specific inotropic effect of alloimmune lymphoid cells on mouse isolated atria"
(1986) Genaro, A.M.;Borda, E.S.;Cremaschi, G.A. (
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)Braun, M. Immunopharmacology. 11(3):129-140
"L-triiodothyronine and imipramine effects on cerebral monoamines in rat and on blood pressure in dog "
(1985) Cicardo, V.H.; Carneiro de Rondina, D.C.; Mastronardi, I.O. Prensa Medica Argentina. 72(7):226-228
"Alloimmunization-induced changes in thymocytes' prostaglandin levels: A signal for the induction of biological activity"
(1985) Borda, E.;Genaro, A.;Peredo, H. (
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)Sterin-Borda, L. International Journal of Immunopharmacology. 7(5):647-653
"Melatonin reverses pinealectomy-induced decrease of benzodiazepine binding in rat cerebral cortex"
(1985) Lowenstein, P.R.; Rosenstein, R.; Cardinali, D.P. Neurochemistry International. 7(4):675-681
"Bradykinin stimulates phospholipase C in rat renal medullary slices"
(1985) Speziale, N.; Speziale, E.H.; Pasquini, J.M. Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 836(1):14-18
"Alterations in the prolactin secretion in streptozotocin-induced diabetic rats. Correlation with pituitary and hypothalamus estradiol receptors"
(1985) Tesone, M.; Ladenheim, R.G.; Charreau, E.H. Molecular and Cellular Endocrinology. 43(2-3):135-140
"Non-cholinergic inotropic responses evoked by electric field stimulation in the isolated rat urinary bladder. Possible participation of substance P"
(1985) Dveksler, G.; Gimeno, M.F.; Gimeno, A.L. Pharmacological Research Communications. 17(12):1109-1119
"Bacitracin increases size of parasporal crystals and spores in Bacillus thuringiensis"
(1985) García-Patrone, M. Molecular and Cellular Biochemistry. 68(2):131-137
"Biologic profile of leukotrienes and other products of lipoxygenases "
(1985) Gimeno, A. Acta Physiologica et Pharmacologica Latinoamericana. 35(1):67-92
"Influence of sex hormones on prostaglandin dehydrogenase activity in the rat uterus"
(1985) Franchi, A.M.; Faletti, A.; Gimeno, M.F.; Gimeno, A.L. Prostaglandins. 29(6):953-960
"Mechanism of hexachlorobenzene-induced porphyria in rats. Effect of phenobarbitone pretreatment"
(1984) Wainstok de Calmanovici, R.; Del Rios de Molina, C.M.; Taira de Yamasato, M.C. Biochemical Journal. 218(3):753-763
"Progesterone in vitro and the output of prostaglandin F from the uterus of ovariectomized rats. Priming or withdrawal?"
(1984) Gimeno, A.L.; Franchi, A.M.; González, E.T.; Gimeno, M.F. Prostaglandins, Leukotrienes and Medicine. 14(2):289-296
"Lipoxygenase inhibitors alter aggregation and adhesiveness of human blood platelets from aspirin-treated patients"
(1983) Gimeno, M.F.;Shattner, M.A.;Borda, E. (
...
)Lazzari, M.A. Prostaglandins, Leukotrienes and Medicine. 11(1):109-119
"Is there a role for dopamine in the regulation of motility of sow oviducts?"
(1983) Chaud, M.;Pardal, J.F.;Viggiano, M. (
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)Gimeno, A.L. Pharmacological Research Communications. 15(10):923-936
"Effect of progesterone on the spontaneous motility and prostaglandin synthesis in uterine horns isolated from ovariectomized rats"
(1982) Franchi, A.M.; Bonacossa, A.; Gimeno, M.F.; Gimeno, A.L. Prostaglandins. 23(6):819-832
"Mechanism of the hypotensive action of prostaglandins A2 and E2 "
(1981) Cicardo, V.H. Acta Physiologica Latino-Americana. 31(2):85-91
"Similar regulatory mechanism underlying 3H-noradrenaline release from isolated hypothalamus and perfused tail artery of the rat by Latrodectus antheratus (black widow spider) venom gland extract and by potassium"
(1981) Pardal, J.F.; Granata, A.R.; Gimeno, A.L.; Barrio, A. Toxicon. 19(2):249-254
"Tryptophan (Trp), serotonin (5-HT), monoamino oxidase (MAO) and 5-hydroxyindole acetic acid (5-HIAA) in brain and subesophagic ganglions of earthworms. Effects of Parathion"
(1979) Izquierdo, J.A.;Rabiller, G.;Borghi, E. (
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)Justel, E. Experientia. 35(1):73-74
"Effects of castration, estradiol and testosterone on tubulin levels of the medial basal hypothalamus and the adenohypophysis of the rat"
(1979) Valenti, C.; Vacas, M.I.; Cardinali, D.P. Experientia. 35(1):120-122
"Central and peripheric mechanism of hypotension produced by dl-propranolol in the dog "
(1978) Cicardo, V.H. Acta Physiologica Latino-Americana. 28(6):235-242
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