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drug targeting
50
"Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer" (2019) Garrido, M.F.;Martin, N.J.-P.;Bertrand, M. (...)Chauchereau, A. Clinical Cancer Research. 25(2):710-723
"The Role of the Phosphorus Atom in Drug Design" (2019) Rodriguez, J.B.; Gallo-Rodriguez, C. ChemMedChem. 14(2):190-216
"Target-Pathogen: A structural bioinformatic approach to prioritize drug targets in pathogens" (2018) Sosa, E.J.;Burguener, G.;Lanzarotti, E. (...)Fernández Do Porto, D. Nucleic Acids Research. 46(D1):D413-D418
"Histamine H4 receptor as a novel therapeutic target for the treatment of Leydig-cell tumours in prepubertal boys" (2018) Abiuso, A.M.B.;Varela, M.L.;Haro Durand, L. (...)Mondillo, C. European Journal of Cancer. 91:125-135
"Targeting the mitochondrial VDAC in hepatocellular carcinoma using a polyclonal antibody-conjugated to a nitrosyl ruthenium complex" (2018) Ramos, L.C.B.;Rodrigues, F.P.;Biazzotto, J.C. (...)da Silva, R.S. Journal of Biological Inorganic Chemistry. 23(6):903-916
"Chronic expression of wild-type Ret receptor in the mammary gland induces luminal tumors that are sensitive to Ret inhibition" (2018) Gattelli, A.;García Solá, M.E.;Roloff, T.C. (...)Hynes, N.E. Oncogene. 37(29):4046-4054
"The druggable pocketome of Corynebacterium diphtheriae: A new approach for in silico putative druggable targets" (2018) Hassan, S.S.;Jamal, S.B.;Radusky, L.G. (...)Azevedo, V.A.C. Frontiers in Genetics. 9(FEB)
"Thyroid hormones and their membrane receptors as therapeutic targets for T cell lymphomas" (2016) Cremaschi, G.A.;Cayrol, F.;Sterle, H.A. (...)Barreiro Arcos, M.L. Pharmacological Research. 109:55-63
"Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase" (2016) Rodriguez, J.B.; Falcone, B.N.; Szajnman, S.H. Expert Opinion on Drug Discovery. 11(3):307-320
"Driving CARs into Sweet Roads: Targeting Glycosylated Antigens in Cancer" (2016) Blidner, A.G.; Mariño, K.V.; Rabinovich, G.A. Immunity. 44(6):1248-1250
"Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases" (2014) Wan, X.;Corn, P.G.;Yang, J. (...)Navone, N.M. Science Translational Medicine. 6(252)
"Acridones as antiviral agents: Synthesis, chemical and biological properties" (2013) Sepúlveda, C.S.;Fascio, M.L.;García, C.C. (...)Damonte, E.B. Current Medicinal Chemistry. 20(19):2402-2414
"A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease" (2013) Laderach, D.J.;Gentilini, L.D.;Giribaldi, L. (...)Rabinovich, G.A. Cancer Research. 73(1):86-96
"Vascular galectins: Regulators of tumor progression and targets for cancer therapy" (2013) Thijssen, V.L.; Rabinovich, G.A.; Griffioen, A.W. Cytokine and Growth Factor Reviews. 24(6):547-558
"Tumor-specific MAGE proteins as regulators of p53 function" (2012) Ladelfa, M.F.;Peche, L.Y.;Toledo, M.F. (...)Monte, M. Cancer Letters. 325(1):11-17
"New antibacterials for the treatment of toxoplasmosis; A patent review" (2012) Rodriguez, J.B.; Szajnman, S.H. Expert Opinion on Therapeutic Patents. 22(3):311-333
"FKBP51 and FKBP52 in signaling and disease" (2011) Storer, C.L.;Dickey, C.A.;Galigniana, M.D. (...)Cox, M.B. Trends in Endocrinology and Metabolism. 22(12):481-490
"Emerging pharmacotherapy of tinnitus" (2011) Langguth, B.; Elgoyhen, A.B. Expert Opinion on Emerging Drugs. 16(4):603-606
"Novel therapeutic targets for arenavirus hemorrhagic fevers" (2011) Garca, C.C.; Seplveda, C.S.; Damonte, E.B. Future Virology. 6(1):27-44
"Acute modulation of calcium currents and synaptic transmission by gabapentinoids" (2010) Uchitel, O.D.; Di Guilmi, M.N.; Urbano, F.J.; Inchauspe, C.G. Channels. 4(6)
"Inhibition of Junín virus replication by small interfering RNAs" (2009) Artuso, M.C.;Ellenberg, P.C.;Scolaro, L.A. (...)García, C.C. Antiviral Research. 84(1):31-37
"Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas" (2009) Labeur, M.; Paez-Pereda, M.; Arzt, E.; Stalla, G.K. Reviews in Endocrine and Metabolic Disorders. 10(2):103-109
"Structure-activity relationships of neuroactive steroids acting on the GABAA receptor" (2009) Veleiro, A.S.; Burton, G. Current Medicinal Chemistry. 16(4):455-472
"Molecular mechanisms of action of some immunosuppresive drugs " (2008) Liberman, A.C.; Druker, J.; Refojo, D.; Arzt, E. Medicina. 68(6):455-464
"Synthesis of 4-azasteroids by an intramolecular Ugi reaction" (2008) Alonso, F.; Acebedo, S.L.; Bruttomesso, A.C.; Ramírez, J.A. Steroids. 73(12):1270-1276
"Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase" (2008) Szajnman, S.H.;García Liñares, G.E.;Li, Z.-H. (...)Rodriguez, J.B. Bioorganic and Medicinal Chemistry. 16(6):3283-3290
"Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer" (2008) Salatino, M.;Croci, D.O.;Bianco, G.A. (...)Rabinovich, G.A. Expert Opinion on Biological Therapy. 8(1):45-57
"Trypanosoma cruzi: Transport of essential metabolites acquired from the host " (2008) Pereira, C.A.;Carrillo, C.;Miranda, M.R. (...)Canepa, G.E. Medicina. 68(5):398-404
"Zn finger containing proteins as targets for the control of viral infections" (2007) García, C.C.; Damonte, E.B. Infectious Disorders - Drug Targets. 7(3):204-212
"Participation of epididymal cysteine-rich secretory proteins in sperm-egg fusion and their potential use for male fertility regulation" (2007) Cohen, D.J.;Da Ros, V.G.;Busso, D. (...)Cuasnicú, P.S. Asian Journal of Andrology. 9(4):528-532
"An insight on targets and patented drugs for chemotherapy of chagas disease" (2007) Duschak, V.G.; Couto, A.S. Recent Patents on Anti-Infective Drug Discovery. 2(1):19-51
"Progresses in the field of drug design to combat tropical protozoan parasitic diseases" (2006) García Liñares, G.E.; Ravaschino, E.L.; Rodriguez, J.B. Current Medicinal Chemistry. 13(3):335-360
"CRF signaling: molecular specificity for drug targeting in the CNS" (2006) Arzt, E.; Holsboer, F. Trends in Pharmacological Sciences. 27(10):531-538
"Nucleoside phosphorylases" (2006) Lewkowicz, E.S.; Iribarren, A.M. Current Organic Chemistry. 10(11):1197-1215
"Arenavirus Z protein as an antiviral target: Virus inactivation and protein oligomerization by zinc finger-reactive compounds" (2006) García, C.C.;Djavani, M.;Topisirovic, I. (...)Damonte, E.B. Journal of General Virology. 87(5):1217-1228
"Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase" (2005) Szajnman, S.H.; Ravaschino, E.L.; Docampo, R.; Rodriguez, J.B. Bioorganic and Medicinal Chemistry Letters. 15(21):4685-4690
"Signaling processes in tumoral neuroendocrine pituitary cells as potential targets for therapeutic drugs" (2005) Paez-Pereda, M.;Giacomini, D.;Echenique, C. (...)Arzt, E. Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5(3):259-267
"Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons" (2005) Gonzalez, S.L.;Labombarda, F.;Gonzalez Deniselle, M.C. (...)De Nicola, A.F. Journal of Steroid Biochemistry and Molecular Biology. 94(1-3 SPEC ISS):143-149
"New perspectives in the treatment of cushing's syndrome" (2004) Labeur, M.; Arzt, E.; Stalla, G.K.; Péz-Pereda, M. Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 4(4):335-342
"Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer " (2004) Salatino, M.;Schillaci, R.;Proietti, C.J. (...)Elizalde, P.V. Medicina. 64(2):129-134
"Specific molecular targets to control tropical diseases" (2001) Rodriguez, J.B. Current Pharmaceutical Design. 7(12):1105-1116
"Glycoinositolphospholipids, free and as anchors of proteins, in trypanosoma" (2001) de Lederkremer, R.M.; Bertello, L.E. Current Pharmaceutical Design. 7(12):1165-1179
"Trypanosoma cruzi arginine kinase characterization and cloning. A novel energetic pathway in protozoan parasites" (2000) Pereira, C.A.;Alonso, G.D.;Paveto, M.C. (...)Flawiá, M.M. Journal of Biological Chemistry. 275(2):1495-1501
"Synthesis of two isosteric phosphono analogues of D-galactofuranosyl phosphate" (1999) Kovensky, J.; Cirelli, A.F.; Sinay, P. Carbohydrate Letters. 3(4):271-276